Prof. Dr. Peter Friedl

Using multi-parametric micorscopy we will undertake a cell-based journey through tissues and organs, and thereby study how shape and space define cell movement in health and disease. As examples, we will monitor the tissue conditions and principles that allow tumor cells to invade tissue and metastasize, and immune cells to attack and combatting tumor cells. Besides complex cell culture models and molecualr research in vitro, I will provide colorful insights into the living organism using intravital microscopy, and highlight the interaction between malignent tumor cell and healthy body, including the resulting malfunctioning of tissue and tissue destruction. In a final chapter, we will also investigate how moderm imaging allows to see the immune system at work, here how a malignant process can be reverted by immunotherapy. 

Curriculum Vitae

Prof. Dr. med. Ph.D. (CDN) Peter Friedl studied at the university of Regensburg, Wurzburg and Bochum human medicine, followed by a dissertation about Immunology and Cell Biology at McGill University in Montreal, Canada. After a period of experimental research at the University of Witten/Herdecke he worked as clinical and scientific assistant at the Clinical Residency of the University of Wurzburg, from 1996 till 2007. In the end of this period he also became head of department. Since 2007 he is the leader of the center of microscopical imaging at Radboud University Nijmegen, Netherlands, and since 2011 the leader of a laboratory for tumor-imaging at MD Anderson Cancer Center in Houston, USA. His work concentrates on dynamic imaging of immune defense and cancer, especially the movement of immune cells, the metastasizing of cancer and the killing of tumor cells through and by the immune system and the resulting therapy methods to heal the tumor. Furthermore he published a lot of international paper about the visualizing of cell functions and he was conventional engaged to forms and limits of scientific perception (f.e. in Friedl, P. 1994. Das physikalische Weltbild der naturwissenschaftlichen Medizin. Erfahrungsheilkunde 43:660-664). For his work about imaging of immune and tumor cells he was honored with a lot of different awards, for example the Felix-Wankel-Tierschutzpreis (1994), the Deutschen Hautkrebspreis (2005), the Deutschen Krebspreis (2008) and the Vici Award of the Netherlandish  Research Community (2010).